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Research


Advancing cystic fibrosis knowledge and care is a vital aspect of The Cystic Fibrosis Institute. CFI, in conjunction with The Cystic Fibrosis Center  of Chicago, is active in the worldwide CF community and can offer clinical research studies that are testing the latest treatments for people with CF. By participating in independent studies, federally sponsored NIH research, or pharmaceutical-based multi-center clinical trials, CFI is helping to discover and develop new and more effective treatment strategies in order to improve the health of people with CF. Dr. Boas and his colleagues have published their research findings in many prestigious national and international medical journals.


Independent CF Research

  • Quality Improvements In CF Health Care Delivery
  • Factors limiting Anaerobic Exercise
  • Exercise recommendations for CF
  • Parental attitudes about exercise
  • Energy metabolism during exercise
  • Exercise induced immune modulation
  • Vascular endothelial growth factor
  • CF Gene analysis and exercise
  • Breathing patterns during exercise

 

Nationally Funded CF Research

  • Growth Hormone Use
  • Inhalational  Antibiotics-Aztreonam
  • Genetic Modifiers
  • Epidemiologic study of CF (Registry)
  • Stool elastase
  • CF Twins-Genetic Analysis
  • The Role of Zithromax in CF
  • CF and the RSV vaccine
  • Exercise, Cytokines, and Growth factors
  • Use of Pulmozyme in young children
  • CT and inflammatory markers in CF
  • Non tuberculous infection in CF
  • Inhaled Levaquin
  • Denufosol in CF
  • Tobramycin I Fosfomycin for Inhalation
  • Pancreatic Enzymes
  • Inhaled Vancomycin
  • Anti-Pseudomonal antibodies
  • Inhaled Ciprofloxacin
  • Small molecule therapy for CF (Ivacaftor)
  • Inhaled Mannitol 

Research presented at national and international meetings including:

  • American Thoracic Society
  • American College of Sports Medicine
  • North American Cystic Fibrosis Annual Meeting
  • North American Society Pediatric Exercise Medicine
  • American Academy of Pediatrics

 

 

 

 

 


Center for Clinical Trials

The Cystic Fibrosis Institute is committed to make available all therapies to people with CF whether already on the market or in research trials. The Clinical Trials Center is a means of overcoming barriers to research participation.  The CFI Center for Clinical Trials provides individuals with CF the opportunity to participate in Phase II, III and IV clinical trials. The center’s staff has extensive experience in research sponsored by the National Institute of Health, the Cystic Fibrosis Foundation, and Pharmaceutical companies.

Dr. Boas is a Board Certified Pediatric Pulmonologist and Associate Professor at Northwestern University Feinberg School of Medicine. As medical director of the center, he is personally responsible for oversight of all studies to ensure the safety to the participants.  

Nadia, Marissa, Karen, and Leigh serve as Research Coordinators. They provide a vast amount of experience with the performance of clinical trials andhave been successful in the completion of over 20 separate trials.

Barriers to participation in clinical research are common.

Do any of the following sound familiar?

"I don't want my child to miss school."

"Let someone else do it."

"Can't I just get the medicine without being in the study?"

"I have to work ."

"I hate hospitals."

" I'm lazy."

It is difficult for anyone to participate in clinical trials. The CFI Center for Clinical Trials understands these issues and is offering a unique program to enhance participation for all who qualify for study.  Specifically, the Center offers clinical trials with:

  • Saturday and evening hours.
  • Availability to anyone with CF who qualifies regardless of where clinical care is given.
  • Dedicated and experienced research staff.
  • Reimbursement for time and travel expenses.
  • Study medications that are free to the participant.
  • Warm and friendly environment without the hassles of traveling to a hospital.
  • Easy parking.
  • Convenient locations accessible by highways without city driving.

 

CFI is a 501(c)3 not for profit organization founded in 2003.